Crossing offers one medication: compounded tirzepatide with vitamin B6. Here is what the B6 is doing in there and how to read your vial.

Vitamin B6 (pyridoxine HCl) is commonly used in compounded tirzepatide formulations. It supports protein metabolism, immune function, and mood, and it may help reduce nausea, one of the most common side effects when starting tirzepatide or moving up a dose.

B6 does not change the safety, effectiveness, or intended use of your tirzepatide.

Because the vial contains two ingredients, the label lists two lines: one for tirzepatide and one for B6. Each shows its own total amount and concentration.

Only the tirzepatide line matters for dosing. The B6 content does not change how many units you draw. If the label says something like 20 mg/mL for tirzepatide, that is the number you use.

The solution looks clear to slightly yellow. That is normal for the B6 formulation.

Our standard formulation includes B6, and additive-free tirzepatide is a clinical pathway, not a preference option. If you have a known allergy or sensitivity to B vitamins, tell us on your intake questionnaire (or message us if you are already a member). Your clinician will review it and determine the right option for you.

If you are unsure whether a past reaction counts, mention it anyway. Better to flag it and let your clinician decide.