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How the increasing-dose plan works

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Written by Matt Brice

Tirzepatide starts low and goes up gradually. That is the whole idea behind the increasing-dose plan: starting low and slow lets your body adapt, cuts down on side effects like nausea, and sets you up for better long-term results.

The dose ladder

Tirzepatide doses run from 2.5 mg up to 15 mg, injected once a week:

  • 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, 15 mg

You start at 2.5 mg and stay at each level for at least 4 weeks. If you are tolerating it well, your provider moves you up to the next dose. Every increase is made with your provider, not on your own.

Finding your maintenance dose

You do not have to climb all the way to 15 mg. The goal is the lowest dose that works for you. Once your weight is moving (or you have hit your goal), you and your provider can hold at your current dose. Stay there about 4 weeks and confirm your weight is stable, then keep going at that maintenance dose.

One price at every dose

At Crossing, every dose costs the same: $149 per month, flat. There is no package to select and no price change when your dose goes up or when you hold at maintenance. Your plan just continues.

A few ground rules

  • Expect gradual progress early on; meaningful results often take a few months

  • Never change your dose on your own. Message your provider through your Crossing account first

  • Feeling rough on a new dose, or sick with vomiting? Message your provider before your next injection

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